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2022年1月13日,，歐盟食品安全局就一種環(huán)麥芽糊精葡聚糖轉(zhuǎn)移酶（cyclomaltodextrin glucanotransferase）的安全性評價(jià)發(fā)布意見,。

據(jù)了解，這種食品酶是由Anoxybacillus caldiproteolyticus菌株St-88生產(chǎn)的,，旨在用于糖基化甜菊醇糖苷的生產(chǎn)中,。

經(jīng)過評估,，專家小組認(rèn)為，在預(yù)期的使用條件下,，不能排除飲食暴露引起過敏和誘發(fā)反應(yīng)的風(fēng)險(xiǎn),，但這種情況發(fā)生的可能性很低。根據(jù)所提供的數(shù)據(jù),，專家小組得出結(jié)論,，該食品酶在預(yù)期的使用條件下不會引起安全隱患。

部分原文報(bào)道如下：

The food enzyme cyclomaltodextrin glucanotransferase ((1→4)-α-d-glucan 4-α-d-[(1→4)-α-d-glucano]-transferase (cyclising), EC 2.4.1.19) is produced with Anoxybacillus caldiproteolyticus strain St-88 by PureCircle USA. It is intended to be used in the manufacture of glycosylated steviol glycosides. Residual amounts of total organic solids are removed by the purification steps applied during the production of the modified steviol glycosides; consequently, dietary exposure was not calculated. For the same reason, toxicological studies other than assessment of allergenicity were not considered necessary. Similarity of the amino acid sequence of the food enzyme to those of known allergens was searched and four matches were found. The Panel considered that, under the intended conditions of use, the risk of allergic sensitisation and elicitation reactions by dietary exposure cannot be excluded, but the likelihood is considered to be low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.